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Tomohisa Takagi Selected Research

guar gum (guaran)

5/2022Water-soluble dietary fiber alleviates cancer-induced muscle wasting through changes in gut microenvironment in mice.
5/2021Partially hydrolyzed guar gum attenuates non-alcoholic fatty liver disease in mice through the gut-liver axis.
7/2020Characterizing the gut microbiota in females with infertility and preliminary results of a water-soluble dietary fiber intervention study.
10/2016Partially hydrolysed guar gum ameliorates murine intestinal inflammation in association with modulating luminal microbiota and SCFA.
1/2016Identification of cysteinylated transthyretin, a predictive biomarker of treatment response to partially hydrolyzed guar gum in type 2 diabetes rats, by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry.
6/2006Partially hydrolyzed guar gum down-regulates colonic inflammatory response in dextran sulfate sodium-induced colitis in mice.

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Tomohisa Takagi Research Topics

Disease

50Inflammation (Inflammations)
10/2022 - 01/2002
43Colitis
10/2022 - 01/2002
31Neoplasms (Cancer)
05/2022 - 01/2003
21Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
07/2020 - 01/2002
20Ischemia
03/2022 - 01/2002
15Stomach Neoplasms (Stomach Cancer)
08/2021 - 01/2002
13Reperfusion Injury
03/2022 - 01/2002
11Ulcer
01/2021 - 03/2006
10Ulcerative Colitis
06/2022 - 12/2008
8Hemorrhage
01/2021 - 01/2004
8Hyperthermia
07/2014 - 11/2003
7Esophageal Neoplasms (Esophageal Cancer)
06/2022 - 08/2016
7Wounds and Injuries (Trauma)
01/2022 - 07/2009
7Dysbiosis
08/2021 - 03/2016
7Colonic Neoplasms (Colon Cancer)
06/2013 - 01/2003
6Body Weight (Weight, Body)
01/2022 - 01/2002
6Pancreatic Neoplasms (Pancreatic Cancer)
01/2020 - 05/2009
6Carcinogenesis
03/2018 - 01/2002
6Stomach Ulcer (Gastric Ulcer)
01/2018 - 07/2010
5Gastritis
01/2022 - 05/2004
5Neoplasm Metastasis (Metastasis)
01/2020 - 01/2003
5Colorectal Neoplasms (Colorectal Cancer)
11/2018 - 08/2010
5Insulin Resistance
01/2016 - 05/2007
5Enteritis
04/2013 - 01/2006
4Irritable Bowel Syndrome (Syndrome, Irritable Bowel)
05/2022 - 12/2017
4Esophageal Squamous Cell Carcinoma
05/2022 - 01/2016
4Adenocarcinoma
01/2022 - 02/2005
4Infections
01/2019 - 12/2009
4Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
07/2016 - 07/2005
4Hypoxia (Hypoxemia)
03/2006 - 06/2003
3Neutropenia
06/2022 - 12/2018
3Carcinoma (Carcinomatosis)
08/2021 - 05/2009
3Disseminated Intravascular Coagulation
08/2021 - 08/2006
3Metabolic Syndrome (Dysmetabolic Syndrome X)
05/2021 - 04/2013
3Non-alcoholic Fatty Liver Disease
05/2021 - 07/2019
3Type 2 Diabetes Mellitus (MODY)
01/2020 - 04/2008
3Peptic Esophagitis (Reflux Esophagitis)
12/2010 - 07/2005

Drug/Important Bio-Agent (IBA)

25CytokinesIBA
06/2022 - 01/2002
20Proteins (Proteins, Gene)FDA Link
03/2018 - 01/2002
16Messenger RNA (mRNA)IBA
01/2022 - 01/2002
16Sulfonic AcidsIBA
11/2021 - 03/2006
14Carbon MonoxideIBA
03/2022 - 04/2009
14Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2021 - 01/2002
13Dextran SulfateIBA
01/2022 - 01/2002
13Peroxidase (Myeloperoxidase)IBA
05/2021 - 04/2004
12Indomethacin (Indometacin)FDA LinkGeneric
02/2014 - 01/2006
10NF-kappa B (NF-kB)IBA
05/2009 - 01/2002
8Heme Oxygenase-1IBA
03/2022 - 12/2008
8Pharmaceutical PreparationsIBA
05/2021 - 11/2002
8Thiobarbituric Acid Reactive SubstancesIBA
01/2021 - 04/2004
8Biomarkers (Surrogate Marker)IBA
05/2019 - 05/2004
7Glucose (Dextrose)FDA LinkGeneric
01/2022 - 05/2007
7Therapeutic UsesIBA
01/2021 - 08/2006
7sodium sulfate (sodium bisulfate)FDA LinkGeneric
07/2020 - 08/2004
7Dextrans (Dextran)FDA Link
07/2020 - 08/2004
7Phenobarbital (Luminal)FDA Link
07/2019 - 01/2002
7LigandsIBA
05/2019 - 01/2002
6Lansoprazole (Prevacid)FDA LinkGeneric
05/2022 - 10/2004
6Proton Pump InhibitorsIBA
05/2022 - 01/2006
6guar gum (guaran)IBA
05/2022 - 06/2006
6Transcription Factors (Transcription Factor)IBA
01/2022 - 04/2003
6Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
02/2014 - 03/2008
5Fluorouracil (Carac)FDA LinkGeneric
06/2022 - 03/2017
5sym-trinitrobenzeneIBA
11/2021 - 08/2013
5Bile Acids and Salts (Bile Acids)IBA
07/2021 - 03/2016
5ZincIBA
07/2020 - 11/2002
5Pioglitazone (Actos)FDA Link
03/2011 - 01/2002
5Hemoglobins (Hemoglobin)IBA
01/2011 - 05/2003
5PPAR gammaIBA
04/2004 - 01/2002
4Interleukin-8 (Interleukin 8)IBA
06/2022 - 01/2002
4Dietary FiberFDA Link
05/2022 - 01/2016
4SolutionsIBA
01/2022 - 08/2012
4Carotenoids (Carotene)IBA
08/2020 - 04/2008
4polaprezinc (Z 103)IBA
07/2016 - 11/2002
4rebamipideIBA
12/2012 - 03/2008
4DNA (Deoxyribonucleic Acid)IBA
01/2010 - 11/2003
4Nitric Oxide (Nitrogen Monoxide)FDA Link
12/2008 - 01/2002
3Peptides (Polypeptides)IBA
10/2022 - 01/2016
3pegfilgrastim (Neulasta)FDA Link
06/2022 - 12/2018
3Docetaxel (Taxotere)FDA Link
06/2022 - 12/2018
3Cisplatin (Platino)FDA LinkGeneric
06/2022 - 12/2018
3Volatile Fatty AcidsIBA
05/2022 - 03/2016
3AcidsIBA
08/2021 - 12/2012
3Peroxisome Proliferator-Activated Receptors (PPAR)IBA
11/2019 - 01/2010
3Drinking WaterIBA
01/2019 - 05/2003
3GemcitabineFDA Link
03/2017 - 05/2009
3CarnosineIBA
07/2016 - 11/2002
3Insulin (Novolin)FDA Link
01/2016 - 05/2007
3Interleukin-6 (Interleukin 6)IBA
12/2015 - 08/2004
3AdiponectinIBA
04/2013 - 03/2008
3Heat-Shock Proteins (Heat-Shock Protein)IBA
07/2011 - 01/2011
3Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
08/2010 - 05/2004
3Reactive Oxygen Species (Oxygen Radicals)IBA
07/2010 - 01/2004
3Free RadicalsIBA
03/2008 - 04/2004

Therapy/Procedure

23Therapeutics
06/2022 - 01/2002
12Lasers (Laser)
01/2022 - 03/2014
11Drug Therapy (Chemotherapy)
06/2022 - 11/2007
8Enema (Enemas)
01/2021 - 03/2006
3Immunotherapy
03/2017 - 07/2011
3Oral Administration
10/2016 - 08/2013